After being troubled by injuries mostly this season, the Belgian is expected to find a new club for next season after talks of a new contract broke down earlier this year between him and his club.
Rumours have it that Chelsea has joined the frame of clubs who wants the defender's services in the summer.
Manchester United, Paris saint germaine and Barcelona are also linked with the former Rojiblancos defender whose contract with Tottenham ends 2019 with a release clause of £25million.
The London club hope to replace both David Luiz and Tim Cahill with the Belgium International in other to bolster their defence line. But Pochettino's side are unwilling to sell the player to a direct rivals in the league and prefer selling the defender abroad.