Deportivo La Coruna are already without Florin Andone for the weekend's action against Barcelona, but Joselu could be another man struggling to get the green light for fitness against Luis Enrique's side.
The Spanish forward has got a groin complaint, forcing him to train away from the group on Friday and with a physio instead, with his inclusion in their match day squad hinges on how the injury develops.
Guilherme dos Santos is also absent for Depor, with Sidnei similarly struggling with injury problems picked up against Real Betis last time out, while Pedro Mosquera is out due to suspension.
Raul Albentosa should come into the heart of the defence for the underdogs, with Alex Bergantinos getting a rare start in the middle of midfield, with the latter yet to even start a game so far during this LaLiga campaign.
If Joselu isn't fit enough to start up top against Barcelona, Pepe Mel might be forced to use Manchester City loanee Marlos Moreno from the off.