Real Madrid are set to miss two of their main players for months, their midfielder Isco Alarcon could be going under the knife after being diagnosed with acute appendicitis.
The Los Blancos released an official statement about the Spanish midfielder on Tuesday afternoon, revealing that he has "undergone successful surgery" at the Hospital La Moraleja in Madrid, having been a surprise absentee from Los Blancos' final training session ahead of Wednesday's league fixture at Sevilla.
Another star player missing from the squad that will face Sevilla on Wednesday is right fullback Dani Carvajal as he missed Tuesday’s training session at the Valdebebas which is another opportunity for Alvaro Odriozola and Nacho Fernandez is to take up the position, the former made his debut for the Galacticos against Espanyol after Carvajal was missing and will be hoping to do the same against Sevilla in a Laliga midweek fixture.
While the absence of Isco, who featured in the Real Madrid starting line-ups for both the UEFA Champions League game against Roma and the home LaLiga Santander win over Catalan side Espanyol but was substituted on 78 minutes, opens the door to emerging star Dani Ceballos, who has impressed in his appearances this campaign.
Toni Kroos should return to the side, although it is possible that 'The Best' award winner Luka Modric is rested for the midweek match. The Croatian was collecting his award on Monday evening in London and had a chance to pose with it ahead of Tuesday's training.
Real Madrid should welcome back the likes of Gareth Bale and Marcelo who were both on the bench for the last outing at the Estadio Santiago Bernabéu in what looks to be a revolving Madrid line-up. It's expected that both will return to the XI for Sevilla.

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