James Rodriguez and Isco are severe doubts for Real Madrid's LaLiga face-off with Sevilla on Sunday after neither midfielder joined up with the squad for full training ahead of the match.
Sitting out the midweek Copa del Rey draw against the Rojiblancos, both are struggling with knocks and look unlikely to shake them off before the 20:45 CET kick-off.
Fabio Coentrao, who watched Thursday's game from the bench, also missed training on Saturday as Pepe and Gareth Bale worked alone on their own respective injury problems.
Meanwhile, Cristiano Ronaldo and Luka Modric return to the matchday squad after being rested for the Copa clash.
Full Real Madrid matchday squad to face Sevilla:
Keylor Navas, Kiko Casilla, Rubén Yáñez, Carvajal, Danilo, Sergio Ramos, Varane, Nacho, Marcelo, Casemiro, Kroos, Kovacic, Modric, Marco Asensio, Lucas Vázquez, Cristiano Ronaldo, Benzema, Álvaro Morata, Mariano.
After the match, Los Blancos will return from Andalusia early in the morning, leading to Zidane delaying Monday's session until 16:00 CET, ahead of the Copa tie with Celta Vigo.