Jorge Sampaoli will set Sevilla up with a three-man defence at Leicester City on Tuesday night, with Wissam Ben Yedder and Pablo Sarabia also expected to start.
Protecting a 2-1 lead at the King Power Stadium, the Argentine is likely to drop wing-back Mariano in favour of the more attacking Sarabia, alongside Samir Nasri in midfield in an attempt to supply lone striker Ben Yedder.
Radio MARCA report that the starting XI will be as follows: Sergio Rico; Pareja, Rami, Mercado; Sarabia, Escudero; N'Zonzi, Iborra, Nasri; Vitolo, Ben Yedder.