A fully fit squad is something of a novelty for any coach and the Frenchman must decide whether to take Luka Modric and Toni Kroos to Estadio Ipurua, having risked them with a spot on the bench in the midweek win at Paris Saint-Germain.
Furthermore, Cristiano Ronaldo may be rested as Isco and Gareth Bale look likely to come into the team after missing out on a starting spot last time out.
The team head to the Basque Country at 19:00 CET on Friday ahead of Saturday's lunchtime kick-off.
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